In the News

Paper published on qVFM

Together with researchers from Ohio State University and Shanghai, AST co-founders Luis Lesmes and Zhong-Lin Lu published a paper in Frontiers in Neuroscience on "Evaluating the Performance of qVFM in Mapping the Visual Field of Simulated Observers With Eye Diseases". The authors conclude that "The qVFM method can be used to characterize residual vision of simulated ophthalmic patients. The study sets the stage for further investigation with real patients and potential translation of the method into clinical practice."

Paper published on deficits of spatial vision in astigmatism

Together with researchers from Guangzhou and Shanghai, AST co-founder Zhong-Lin Lu published a paper in Frontiers in Psychology on "Meridian-Specific and Post-Optical Deficits of Spatial Vision in Human Astigmatism: Evidences From Psycho-Physical and EEG Scalings".

Review paper published on qCSF in patients with non-neovascular and neovascular age-related macular degeneration

Researchers from Mass Eye and Ear published a review paper in the Journal of Clinical Medicine on "Measuring the Contrast Sensitivity Function in Non-Neovascular and Neovascular Age-Related Macular Degeneration: The Quantitative Contrast Sensitivity Function Test" and conclude that "Using active learning principles, the qCSF can efficiently measure contrast sensitivity across multiple spatial frequencies with both high sensitivity in detecting subtle changes in visual function and robust test–retest reliability, emerging as a promising visual function endpoint in AMD both in clinical practice and future clinical trials."

Paper published on sensitivity and stability of functional vision tests in detecting subtle changes

Together with researchers from Guangzhou, Hong Kong, and Shanghai, AST co-founder Zhong-Lin Lu published a paper in translational vision science & technology on "Sensitivity and Stability of Functional Vision Tests in Detecting Subtle Changes Under Multiple Simulated Conditions". The paper concludes that "Compared with visual acuity and chart-based CS tests, the quick CSF method provided more reliable and sensitive measures to detect small visual changes."

ARVO Meeting features six qCSF- and qVA-related presentations

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Paper on qCSF in amblyopic subjects chosen as Sensory Neuroscience Editor's Pick 2021

Our paper "Binocular Summation and Suppression of Contrast Sensitivity in Strabismus, Fusion and Amblyopia" was included in the Frontiers in Human Neuroscience top-10 list of "well-received spontaneous articles from the past couple of years, which have been specially handpicked by our Chief Editor, Prof. Jae Kun Shim. [...] All research presented here displays strong advances, in theory, experiment, and methodology with applications to compelling problems."

Paper published on qCSF assessments following LASIK and PRK-MMC in treatment of myopia

Researchers from the Naval Medical Center in San Diego used the qCSF to assess vision in 58 active U.S. military service members who elected LASIK or PRK-MMC refractive surgery for myopia treatment. Results were published in Military Medicine, and the researchers conclude that "The standard black-on-white high-contrast, chart-based visual acuity test is weak in predicting quality of vision. The qCSF detects mild-to-moderate visual changes and is suitable for quality of vision assessment following refractive eye surgery."

Paper published on qCSF in patients with macular disease and good visual acuity

Researchers from Mass Eye and Ear published a paper in the British Journal of Ophthalmology on "Contrast sensitivity function in patients with macular disease and good visual acuity" and conclude that "CSF measured with the qCSF active learning method was found to be significantly reduced in eyes affected by macular disease despite good VA compared with healthy control eyes."

Paper published on qCSF assessments in AMD under normal and low luminance conditions

Together with researchers from the Retina Foundation of the Southwest, we published a paper in the American Journal of Ophthalmology on "Normal and Low Luminance Automated Quantitative Contrast Sensitivity Assessment in Eyes with Age-Related Macular Degeneration". Results show that the CSF significantly differs between advancing stages of dry AMD, in particular when measured under low luminance conditions.

Talk at The Macula Society Meeting

Joan W Miller, Mass Eye and Ear, will present her work on "Contrast Sensitivity Function in Non-Neovascular Age-related Macular Degeneration Measured with Active Learning" at The 44th Virtual Annual Macula Society Meeting, February 6-7, 2021. She concludes that "Early nnAMD was associated with reduced qCSF compared to controls as measured by novel active learning method, despite no difference in BCVA."

Paper published on qCSF in Multiple Sclerosis

Together with researchers from Germany, France, and the US, we published a paper in Frontiers Neuroscience that shows the precision of the qCSF in people with Multiple Sclerosis.

qCSF used as visual performance measure in pistol marksmen

US Naval Medical researchers investigated visual performance in pistol marksmen and with different military combat eye protection lenses. Paper accepted in Military Medicine.

Paper published on quantitative Visual Acuity

We published a paper in Translational Vision Science and Technology, evaluating our qVA algorithm against ETDRS and FrACT. The paper was featured on the journal cover page! 2D probability density plot on cover of TVST journal

Paper published on qCSF in retinal detachment

Researchers from Mass Eye and Ear and the Kellog Eye Center published a paper in the Journal of VitreoRetinal Diseases on the qCSF in macula-off retinal detachment.

Paper published on qCSF in retinal vein occlusion

MEEI researchers showed that disorganisation of retinal inner layers is associated with reduced contrast sensitivity in retinal vein occlusion. Their study "highlights CS as an important functional endpoint for prospective clinical trials".

Paper published on active learning in retinal vein occlusion

Researchers from AST, the Kellog Eye Center, and Mass Eye and Ear published a paper in Ophthalmic Surgery, Lasers and Imaging Retina on contrast sensitivity in retinal vein occlusion. The study finds that "CSF seems to be a promising visual function endpoint with potential applications in clinical practice and future clinical trials".

Paper published on effect of age and refractive error on the qCSF

Researchers from Sun Yat-Sen University published a study in Eye.

Paper published on qCSF in a low-vision population

Researchers from the University of Waterloo published an IOVS paper on contrast sensitivity in Para Nordic and Para Alpine skiers.

qCSF discussed as outcome measure in retina and glaucoma

AST CEO Luis Andres Lesmes participated in a European Vision Institute special interest focus group on "New Technologies for Outcome Measures in Retina and Glaucoma". Click "View link" to read the report.

Paper published that investigates the importance of qCSF in glaucoma

Researchers from the Wilmer Eye Institute publish a paper in IOVS.

New method published to map the visual field

In a collaboration with Ohio State University and New York University Shanghai, AST researchers have developed a new method for visual field mapping.

Paper published that compares qCSF and sweep visual evoked potential acuity estimates

Researcher from the Southern California College of Optometry publishes a paper in Documenta Ophthalmologica.

Talk to be presented at 52nd Annual Retina Society Meeting

John Miller, MD, Mass Eye and Ear Infirmary, will present results on "Active Learning of Contrast Sensitivity Deficits in Maculopathy with Good Acuity".

ARVO Meeting features seventeen qCSF- and qVA-related presentations

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Presentation at the European Vision Institute

AST CEO Luis Lesmes will give an invited talk "Bayesian Adaptive Estimation of the Contrast Sensitivity Function" at a meeting of the European Vision Institute's Special Interest Focus Group "New Technologies for Outcome Measures in Retina and Glaucoma". The meeting will be hosted by the Institute of Molecular and Clinical Ophthalmology Basel on November 8th.

ARVO Meeting features eight qCSF- and qVA-related presentations

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Paper on Early Diabetic Retinopathy

Researchers at the Kellog Eye Center of the University of Michigan evaluated OCT imaging, perimetry, e-ETDRS, and the quick CSF method for their effectiveness to diagnose and monitor early diabetic neuroretinal disease. They found that "Contrast sensitivity, as assessed by AULCSF and contrast sensitivity measurements at various spatial frequencies on the AST Platform, was the most sensitive test for detection of subtle functional differences in diabetic patients both with and without retinopathy". The paper is part of a special IOVS issue on "Biomarkers and Surrogate Endpoints in Ophthalmic Clinical Research".

Poster presented at American Academy of Optometry Meeting

US Navy researchers present their work on "Effects on Contrast Sensitivity Function following LASIK & PRK". They find that the "QCSF is a sensitive method in detecting functional visual changes during the recovery after refractive surgery"

Talk at American Society of Retina Specialists

John Miller, Mass Eye and Ear, presents his work on "A Novel Contrast Sensitivity Testing Device as a New Measure of Visual Recovery in Retinal Detachment". Click for a video interview.

Thirteen qCSF-related abstracts to be presented at ARVO 2017

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Ein moderner Sehtest (A modern vision test)

Die Wirtschaft (in German)

Poster presented at American Diabetes Association Meeting

Researchers at the Joslin Diabetes Center, Boston, find that the quick CSF "may be a sensitive method to detect visual function changes resulting from diabetes and diabetic macular edema". Click "View link" for full abstract.

ARVO Meeting features more than a dozen qCSF-related presentations

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A new vision for blind patients

EyeWorld

Die Boston-Lübeck-Connection für bessere Augen-Untersuchungen

Technologie-Blog Lübeck

Children born blind can learn to see as teenagers

Nature

Brain adapts to see after extended blindness

Optometry Today

Despite what you may think, your brain is a mathematical genius

Salk Institute

The Visual System as Economist: Visual Adaptation Studied by Salk and Schepens Scientists

Schepens Eye Research Institute